Traces historical developments in scientific conceptions of physiology, ecology, behavior, and evolutionary biology during the mid-twentieth century

Life Out of Balance focuses on a period in history when new ideas of self-regulation, adaptation, and fitness became central to a variety of biological disciplines. During the decades surrounding World War II, these ideas developed in several quite different contexts and led to greater debates about the merits of such models as applied to larger systems, including society at large. Particularly in its later cybernetic form, homeostasis seemed to provide new ways of discussing balance and regulation that avoided discredited approaches of earlier champions of vitalism and mechanism. It provided a common perspective and terminology for discussing self-regulating “systems,” whether biological, mechanical, or social. Although enormously fruitful and influential, homeostatic perspectives also generated numerous controversies when critics questioned the degree to which biological systems are characterized by balance and self-regulation. Resolving these controversies continues to be a challenge in modern biology.

If natural selection constitutes the first law of biology, scientists who champion homeostasis as a theoretical model claim that it is a second law, equally important and closely related to the first. Such claims notwithstanding, homeostasis has generated a series of controversies since it was formalized by Walter Cannon in the late 1920s. Critics contended that Cannon took a too-optimistic view of life, not only ignoring pathological deviations from normality but also failing to adequately explain the ability of living things to respond adaptively to environmental challenges.

Underlying these controversies was the unresolved problem of integrating physiology and other areas of functional biology with the emerging evolutionary synthesis of Mendelian genetics and Darwinian natural selection. The physiological idea of homeostasis as the adaptive “fit” between the organism and its environment and the Darwinian idea of adaptation and fitness in terms of reproductive success might seem to be complementary in an unproblematic way, but historically they have had an uneasy relationship.
 

The understanding of sound underwent profound changes with the advent of laboratory science in the nineteenth and twentieth centuries. New techniques of sound visualization and detection, the use of electricity to generate sound, and the emergence of computers radically reshaped the science of acoustics and the practice of music. The essays in this volume of Osiris explore the manifold transformations of sound ranging from soundproof rooms to psychoacoustics of seismology to galvanic music to pedaling technique. They also discuss more general themes such as the nature of scientific evidence and the development of instruments and instrumentation. In examining the reciprocity between music and science, this volume reaches a new register in the evolution of scientific methodology during the nineteenth and twentieth centuries.